Kongre Programı

Thursday March 07, 2024
10:00 – 14:00Registration
Opening Ceremony
14:00 – 14:30Prof. Dr. Ramazan ALTUNDAŞ, Chair
İkram CENGİZ, Chair of The Turkish Chemists` Society
Prof. Dr. Hacı Ali MANTAR, Rector, Gebze Technical University
14:30 – 16:30Prof. Dr. Onur Burak DURSUN, Editor of Turkish Rare Disease Action Plan
Prof. Dr. Ramazan ALTUNDAŞ, Gebze Technical University
Doğan TAŞKENT, Atabay
Berkant KÖSEOĞLU, General Manager, Ulkar Kimya
SGK
Uzm. Dr. Musa İLKER, İlaç ve Eczacılık Başkanı Yardımcısı, TITCK
İlaçta Yerelleşme Raporunun Katılımcılar ile Paylaşılması

Yetim İlaçlar
16:30 – 17:00Dr. Fahrettin KOCA, Minister, Republic of Türkiye Ministry of Health (in tensions)
17:00 – 17:30Crystal Mortar Awards Ceremony
17:30 – 18:00Cofee Break
Session 1Session Chair: Dr. Mutlu TOPAL
18:00 – 18:40Dr. Yavuz Gökalp YILDIZ
What should be the Development Parameters of the Pharmaceutical Industry in the 21st Century?
18:40 – 20:30Dinner
Friday March 08, 2024
Session 2Session Chair: Prof. Christa E. MULLER
09:00 – 09:40Prof. Vittorio PACE, University of Turin
Designing New Synthetic Concepts in Medicinal Chemistry with C-1 Sources
09:40 – 10:10Assoc. Prof. Esen BELLUR ATICI, Deva Holding A.S.
Pharmation and Control of Impurities in Pharmaceuticals
10:10 – 10:30Assoc. Prof. Serhan TURKYILMAZ, METU
Cellulose Microspheres Decorated with Zn(II)-Bis(dipicolylamine) Complexes for the Removal of Bacterial Cells from Aqueous Liquids
10:30 – 11:00Coffee Break
Session 3Session Chair: Assoc. Prof. Esen BELLUR ATICI
11:00 – 11:40Dr. Joerg SCHLINGEMANN, Global Quality Control Principal Expert
The Nitrosamine Saga
11:40 – 12:10Assoc. Prof. Ömer Faruk KARATAS, Erzurum Technical University
From molecular pathogenesis to drug design; POFUT1 as a novel therapeutic target for head and neck cancers
12:10 – 12:30Asst. Prof.  Shirin TARBIAT, Uskudar University
The Impact of Lignan Fractions of Piper Cubeba Fruit on Alzheimer’s Disease
12:30 – 14:00Lunch
Session 4Session Chair: Assoc. Prof. Ömer Faruk KARATAS
14:00 – 14:40Prof. Christa E. MULLER, University of Bonn
Medicinal Chemistry of Purinergic Signaling: Targets and Drugs for Cancer Immunotheraphy
14:40 – 15:10Prof. Yusuf TUTAR, University of Health Sciences
Drug Designing Against Cellular Mechanics
15:10 – 15:30Prof. Nurettin MENGEŞ, Necmettin Erbakan University
A New Lead Compound for Glioblastoma and Details of Molecular Mechanism
15:30 – 16:00Coffee Break
Session 5Session Chair: Assoc. Prof. Safacan KOLEMEN
16:00 – 16:40Prof. Engin ULUKAYA, Istinye University
Palladium (II) Based-Anticancer Compounds: A New Hope?
16:40 – 17:10Prof. Serdar DURDAGI, Bahçeşehir University
MOL2DRUG: Developing and Pretesting of a Mobile Application Utilizing Deep Learning QSAR for Predicting Biological Activity and Toxicity of a Molecule from Hand Drawn or Uploaded Images
17:10 – 17:30Assoc. Prof. Hina SIDDIQUI, University of Karachi
Privileged-substructure-based Diversity Oriented Synthesis: Examples of Our Work in the Syntheses of New Chemical Entities and their Biological Studies
17:30 – 17:50Assoc. Prof. Pınar ŞEN, Yeditepe University
Improvement of in Vitro Antimicrobial Activities of Boronic Acid-Functionalized Benzimidazole Derivatives When Conjugated to The Graphene Quantum Dots
17:50 – 18:10Dr. Emrah KAVAK, Necmettin Erbakan University
Synthesis and Characterization of Artesunate-Indole Hybrid Molecules
Session 6Short Oral Presentations

18:30 – 19:30

Session Chair: (Mirage I-II) Prof. Aliye ALTUNDAŞ
Session Chair: (Odeon) Prof. Nermin SIMSEK KUS
Session Chair: (Phoenix I) Prof. Yunus KARA
Session Chair: (Phoenix II) Dr. Emine YURTOĞLU
19:30 – 20:30Dinner
20:30 – 22:30Poster Presentations, Mirage I-II
Saturday March 09, 2024
Session 7Session Chair: Prof. Engin ULUKAYA
09:00 – 09:40Prof. Elia PSILLAKIS, Technical University of Crete
Towards Circular Analytical Chemistry
09:40 – 10:10Andrea SILVESTRI, Analytical Research Manager – Sterling SpA
Challenges in Manufacturing of APIs for Inhalation
10:10 – 10:30Assoc. Prof. Safacan KOLEMEN, Koç University
Hemicyanine Derivatives as Effective Type I Photosensitizers
10:30 – 11:00Coffee Break
Session 8Session Chair: Assoc. Prof. Serhan TURKYILMAZ
11:00 – 11:40Prof. Dr. Bezhan CHANKVETADZE, Tbilisi State University
The Role of Enantioselective Liquid Chromatography in Analysis of Chiral Drugs of Abuse
11:40 – 12:10Prof. Dr. Sibel AYŞIL ÖZKAN, Ankara University
Modern Designs of Molecularly Imprinted Polymers for Electrochemical Sensing and Analysis of Pharmaceuticals
12:10 – 12:30Asst. Prof. Faika BAŞOĞLU ÜNAL, European University of Lefke
Exploring Apoptosis-Inducing Thiosemicarbazides: Novel Synthesis and Anti-Proliferative Evaluation in HEPG2 Cells
12:30 – 14:00Lunch
Young Researcher
Session 9
Session Chair: Prof.  Nurettin MENGEŞ
14:00 – 14:15Aslınur DOĞAN, Adıyaman University
Investigating the Computational and Biochemical Profiles of Bis-Histamine Schiff Bases and Bis-Spinaceamine Substituted Analogues: A Comprehensive Analysis of DNA Cleavage and Enzymatic Activities
14:15 – 14:30Iwona KWIATKOWSKA, Medical University of Bialystok
Proapoptotic activity of MM-129 and indoximod in experimental colon cancer model
14:30 – 14:45Dr. Nazlı FARAJZADEH ÖZTÜRK, Istanbul Technical University
The Role of Phthalocyanines in Nanotechnology
14:45 – 15:00Dr. Toghrul ALMAMMADOV, Koç University
Activity-based molecular sensors for visualization of cancer cells with an improved selectivity
15:00 – 15:15Tuğçe CİNEK, Istanbul Health and Technology University
Synthesis and anticancer activities of 5-nonsubstituted/methyl-2-indolinone derivatives
15:15 – 15:30Pharm. Yaren Nur ZENNİ, Inonu University
Selective MAO-B Inhibitors Bearing Heterocyclic Moieties
15:30 – 16:00Coffee Break
Session 10Session Chair: Assoc. Dr. Azim Ziyaei HALIMEHJANI
16:00 – 16:30Prof. Raid J. ABDEL-JALIL, Sultan Qaboos University
Design and synthesis of novel Positron Emission Tomography (PET) markers
16:30 – 17:00Prof. Erdal BEDIR, IZTECH
Expected a small compound yet encountered supramolecular particles with promising anticancer activity
17:00 – 17:20Asst. Prof. Hande GÜNDÜZ, Koç University
Hydrogen Peroxide Activatable Chemiluminescent Probe for the Detection of Oxidative Stress
17:20 – 17:40Asst. Prof. Nigâr KANTARCI ÇARŞIBAŞI, Üsküdar University
Queuine as a Potential Multi-Target Drug for Alzheimer’s Disease
17:40 – 18:00Asad RIZVI, Abdi İbrahim
Recent advances in Design of Amorphous Solid Dispersions
18:30 – 19:30Dinner
19:30 – 21:30Poster Presentations, Mirage I-II
Sunday March 10, 2024
Session 11Session Chair: Prof. Raid J. ABDEL-JALIL
09:00 – 09:30Assoc. Prof. Azim Ziyaei HALIMEHJANI, Sharif University of Technology
Nitroepoxides as efficient intermediates in Organic Synthesis
09:30 – 10:00Prof. Mükerrem Betül AYCAN YERER, Erciyes University
Current biotechnological approaches in the development of targeted cancer drug candidates
10:00 – 10:20Kadir ALUÇ, Abdi İbrahim
Elucidation of an Impurity After Terminal Sterilization in Sugammadex Sodium Iv By Lc-Ms
10:20 – 10:40Dr. Ümit BABACAN, Akdeniz University
Purification Of Ferulic Acid From Agricultural Wastes Using Feruloyl Esterase Enzyme
10:40-11:00Merve KUCUKOFLAZ KORKMAZ, Erciyes University
Synthesis and Characterization of Functionalized Nanoparticles for Enhanced Enzyme-Free Glucose Sensing in Biosensors
11:00 – 12:00Closing Ceremony and Poster Awards
WORKSHOP PROGRAMME
08 March 2024, Friday

14:00 – 15:00

Paavo SILLANPAA, UPMRAFLATAC
“Managing risk in pharmaceutical labelling”
09 March 2024, Saturday
10:00 – 11:00Uğur FİDANSOY, Terra Lab
“Sentezden Saflaştırmaya İlaç Prosesleri”
11:00 – 12:00Çağla AFŞİN, Ashland
“Klucel™ Xtend Hydroxypropyl Cellulose – Hydrophillic Matrix Polymer Designed to Overcome the Limitations of Traditional Hypromellose Polymers”
Murat IŞIK. Ashland
“Aquarius™ Titanium-Free Coating Systems – Versatile Titanium-Free Coating Systems With İmproved Performance”
14:00 – 15:00Ömer ÖZCAN, LİKROM
Nitrozamin Analizlerine Yaklaşım ve Metot Geliştirme”
15:00 – 16:00Prof. Bekir Faruk ERDEN, Kocaeli University
“Yapay Zeka ve Klinikte İlaç Geliştirme”
16:00 – 17:00Dr. Nesrin Çakır ARICAN, T.C. Tarım ve Orman Bakanlığı
“İlaç Sektöründe Zirai İlaçlar ve Kimyası”
17:00 – 18:00Mustafa Hakan GÖNÜL, Heka
“Sentezden İlaca Giden en Kestirme Yol!”

Mirage I-II Hall

Poster no

Author

Title

OP1

Nurgül GİRGİN

Application of Cation Exchange Chromatography with Linear Gradient Elution for Charge Variants Optimization in mAbdi2 Product

OP2

Öznur ÖZASLAN

Investigation of the Effects of Critical Process Parameters such as Temperature, pH and pCO2 on Charge Variants of mabdi2

OP3

Beyza HAMUR

Synthesis Of Isoxazole-Quinoline Derivatives and Investigation of Inhibitor Effects on Epidermal Growth Factor Receptor

OP4

Göksu ÖZÇELİKAY-AKYILDIZ

Evaluation of electrochemical behavior of Riociguat with bare glassy carbon electrode and MIP-based electrochemical sensor

OP5

İsmail AKÇOK

Design and in silico Studies of Newly Designed Cinnamic Acid/Pyridine Carboxylic Acid and Cinnamic Acid/Pyridine Acetic Acid Derivatives as Potent Class I Histone Deacetylase Enzyme Inhibitors

OP6

Nermin Başak SENTÜRK

Investigation of the Possible Effects of Boron Derivatives on the Pathogenesis of ALS in a Transgenic SOD1 Mouse Model: A Pilot Study

OP7

İbrahim ÇELiK

Synthesis of New Biologically Active Sulfamoyl Urea Derivatives

OP8

Tuğba ÇOPUR

The Effect of Various Coating Parameters on The Characteristics of Blank Plga Nanopartıcles

OP9

Nurdan AKDOĞAN

Synthesis of Some New Heterocyclic Compounds Containing Thiotetrazole Ring and İnvestigation of Their Biological Activities

OP10

Esra PEZİK

The Effect of Different Carriers on In-Vitro Cytotoxicity of Lamotrigine Solid Dispersions

OP11

Halil İbrahim ÖZDEMİR

Optimization of a novel formulation for mAbdi2, a biosimilar monoclonal antibody

OP12

Gülten TIRNAKSIZ

A New Regioselective C-C Coupling Procedure Between Csp3 – Csp3 Functionality

OP13

Bassam A. NAJRİ

Synthesis of Ester-Linked Artesunate-Benzofuran Hybrid Compounds

OP14

Metin YILDIRIM

The Matrix Effect in the Analysis of Some Drug Substances in Urine Samples by Electrospray Ionisation-Liquid Chromatography Tandem Mass Spectrometry

OP15

Merve SAYLAM

Design, Synthesis and Molecular Modelling Studies on 4-(1H-Benzoxazole-2-yl)]-Anilide Derivatives

OP16

Sevinç Ayla ÖZSAR

Investigation of the Interaction Between an Antiparkinson Drug Entacapone and Human Serum Albumin Using Electrochemical and Spectroscopic Methods

OP17

Melik Fırat MENGEŞ

Cyclization Reactions of N-Propargyl-pyrazole-5-carboxylate Derivatives with Hydrazine Hydrate: Experimental and Theoretical Investigations

OP18

Aybek YİĞİT

Green production of silver nanoparticles from the Rumex Patientia L. plant and evaluation of their antibacterial properties

OP19

Aybek YİĞİT

Design, Synthesis, Characterization and Research of Application Areas of New Type COF Materials with ESIPT Emission

OP20

Fatma ALBAYRAK HALAÇ

Synthesis and Biological Evaluation of Novel Imidazo[1,2-a]pyridine Triazole Hybrid Compounds

OP21

Selbi KESKİN

Synthesis of novel 3,5-disubstituted izoxazoles via 1,3-dipolar cycloaddition

OP22

Kemal SOLAKYILDIRIM

Region-Specific Cell Membrane Analysis of Mouse Brain Regions by LC-QTOF-MS

OP23

İrem AKGÜL

Iron-catalyzed N-dealkylation of Tertiary Amines; Synthesis of Drug Metabolites

OP24

Duygu Tuğçe BARAN

Synthesis of Zinc Oxide Nanoparticles (ZnO NPs) by Green Chemistry and Investigation of their Bioactivity on Prostate Cancer Cells using Nuclear Methods

OP25

Muhammed TRAWALLY

Synthesis, FT-IR spectrum, experimental and theoretical crystal studies, and carbonic anhydrase inhibition studies on 2-[(1H-Pyrrol-2-yl)methylidene]-N-(3-sulfamoylphenyl)hydrazine-1-carbothioamide

ODEON 

Poster no

Author

Title

OP26

Merve DOĞAN

Photoredox Driven General Method for Amide Synthesis from Simple and Complex Tertiary Amines via using Different Carboxylic Acids through C-N Bond Cleavage

OP27

Elif DENİZ

Facile Synthesis of Pyrazole-Aldehyde Derivatives and Preparation of Versatile Derivatives with Potential Antiproliferative Effects

OP28

Doğan AKBULUT

Investigation of the Photophysical Properties of Bis(dipicolylamine) Ligand Bearing Porphyrin Derivatives

OP29

Nuray CÖMERT

Lisosom-targeted Cell Imaging with New ESIPT-Based Probes

OP30

Şeyma Gülnaz YARLILAR

Investigation of the Cell Migration Effect of Synthetic Bicyclicepoxide Derivative

OP31

Fatmanur UYAN

Cobalt(II) Complex and Doxorubicin-Based Metal-Organic-Phosphate Frameworks: Biomedical Applications as Drug Delivery Systems 

OP32

Nihan AKTAŞ PEPE

The Effects of Cinnamic Acid and Autophagy Inhibition on Myelination of Co-cultured Cells

OP33

Funda ÖZDEMİR GÜNEY

Synthesis and Characterization of Drug Carrier Silica Nanoparticles for the Development of Sustainable Agricultural Technologies

OP34

Yasemin CAMADAN

Investigation of the Drug Potential of N-(6-Methylpyridin-2-Yl) Glycine by Examining Its Biological Activities

OP35

Shafeek BUHLAK

Enzymatic Resolution Unveiled: A Gateway To Chiral Azaspirodeca and -Undecadienes for Biologically Active Compound Synthesis

OP36

Bilge ÖZCAN

Ca-MPOF Nanoparticles Synthesis, Characterization, and Drug Release Applications

OP37

Rümeysa BEYAN

Cu/Sr-Based Metal Phosphate Organic Framework Synthesis for in vitro Cytotoxic Activity Tests

OP38

Özge KOZGUŞ GÜLDÜ

Preparation and in vitro Investigation of Prostate Specific Membrane Antigen Targeted Mesoporous Silica Nanoparticles on Prostate Cancer Cells

OP39

Salih TUNCAY

Benserazide derivative 2-amino-N’-(4-(dimethylamino)benzylidene)-3-(4-hydroxyphenyl)propanehydrazide Synthesis of Converted Method

OP40

Muhammed Hanifi ÇELİKOĞLU

Selectfluor and Alcohol Mediated Synthesis of Bicyclic Oxyfluorination Compounds by Wagner-Meerwein Rearrangement: A Synthetically Efficient and Novel Method

OP41

Ziya DAĞALAN

Electrochemical C-H Amination of Quinoxalinone Derivatives on Flexible Graphene Paper Electrodes

OP42

Ahmet ÇAĞAN

Synthesis and  Cholinergic Properties of Novel Dopamine Derivatives

OP43

Aslınur DOĞAN

In silico Molecular Docking Study of 1,3,5-Triazine Substituted Sulfonamides for SARS-CoV-2 Active Main Protease

OP44

Aslınur DOĞAN

In Silico and In Vitro Assessment of The Antibacterial Efficacy of Azo-Based Derivatives of 2-Thioxo-Pyrimidine-4,6-Dione

OP45

Saima İKRAM

Development of Dynamic Target-based Pharmacophore Models to Target OX40–OX40L Interaction with Small Therapeutic Molecules

OP46

Nebih LOLAK

In silico and In vitro Antibacterial Potency Evaluation of 1,3-diaryltriazen Substituted Sulfaguanidine Derivatives

OP47

Mine İSAOĞLU

Computational Design and Molecular Dynamics Simulations of Potential Non-Nucleoside Inhibitors Targeting DNA Methyltransferases in Cancer

OP48

Muhammed Ali NALBANT

Effects Of Antioxidant Drugs On Mitochondrial Genes In Hepg2 Cell Line

OP49

Şule GÜRSOY

Synthesis of Chalcone-Pyrrol Hybrid Derivatives and Investigation of Their Antiproliferative Effects

OP50

Şule GÜRSOY

Synthesis of Benzoxazole Derivatives and Investigation of Their mTOR Inhibitor Activities

PHOENİX-I

Poster no

Author

Title

OP51

Suleyman AKOCAK

Sulfamethazine Containing 1,3-diaryltriazen Derivatives: In silico and In vitro Antibacterial Studies

OP52

Suleyman AKOCAK

Exploring the Therapeutic Potential: Antioxidant and Antibacterial Properties of Pyrazolones Incorporating Sulfonamide Moieties

OP53

Zahidul İSLAM

Immunotherapy for the Treatment of Colorectal Cancer: Strategy and Future Prospect

OP54

Ahsen BOLAT

Targeting STAT3 in Cancer Immunotheraphy

OP55

İrem Sena KARAKAŞ

Design, Synthesis and Characterization of Novel Cyano- Pyrazole Derivatives

OP56

Mustafa Z. KAZANCİOGLU

Enzyme inhibition activities and Synthesis of N-propylaniline-phenylpiperazine derivatives

OP57

Havva Berre AYVAZ

Tomatidine and Cisplatin Combination Treatment Synergistically Induces Apoptotic Cell Death and Reduced Cell Viability of FLT3-ITD+ AML Cells

OP58

Sümeyye YÜCETEPE

Synthesis and Structure Elucidation of Some Urea and Chalcone Derivatives Based on 4-Aminoacetophenone

OP59

Merve ŞANSAÇAR

The Inhibition of Histone Deacetylase Enzyme and Spleen Tyrosine Kinase (SYK) on the FLT3(+) Acute Myeloid Cells

OP60

Osman MOLLA

A New Synthetic Methodology for the Synthesis of Chloroquine and Hydroxychloroquine Molecules

OP61

Karina AMUDİ

Alkyl-Onium Salt Catalysts for Alkyne Cyclization: A New Breath for Umpolung Reaction

OP62

Behiye Büşra TAŞBAŞI

Synthesis of a Fluorescent Probe Based on ESIPT Molecules and Evaluation as a Cell Imaging Agent

OP63

Elif Esma GÖNÜL

Ionized Tetracyclic Skeletones for ESIPT-emitted Fluorescent Probes

OP64

Elif GÖKÇAY BİLİCİ

Synthesis of Aromatic Lactones via Keten Addition Reactions and Investigation of their Antioxidant Capacities

OP65

Lale Beril SUBAY

Rapamycin and Niacin Combination Exerts Anti-Cancer Effect Through Activation of Autophagy on Acute Myeloid Leukemia Cells

OP66

İbrahim PINAR

Immunotherapy Approach for Cancer Treatment: Designing of Small Molecules for PD-1/PD-L1 Interaction Inhibition

OP67

Gözde ÇINAR

Design, Synthesis and Anti-coronavirus Evaluation of New Spirothiazolidinone Compounds

OP68

Gözde ÇINAR

Synthesis, Characterization and Antiviral Activity of New Spirothiazolidinone Derivatives Carrying Indole Moiety

OP69

Bilgesu Onur SUCU

Design and Synthesis of Benzofuran/Heterocylic Hybrids as Potential Bioactive Agents

OP70

Efsun KOLATAN

The Importance of Standardization in Laboratory Animal Research

OP71

Esra GÜREL

Synthesis of New Curcumin Compounds Containing O-Alkyl Groups at Phenyl Rings

OP72

Ronak Haj ERSAN

Synthesis and Anticancer Activity of Benzimidazole Derivatives Containing 2-Amide and Ether Bonds

PHOENİX-II

Poster no

Author

Title

OP73

Aslıhan KARA

Synthesis of Ferrocene-Benzofuran-Artemisinin Derivatives

OP74

Emrah POLAT

Investigation of Anti-Cancer Effects of Enantiomerically Pure (S)-4-Aminokinazoline Derivatives on Human Lung (A-549) Cancer Cell Line

OP75

Salma GHAZY

A Novel Algorithm for Virtual Screening of Extensive Small Molecule Libraries Targeting ERCC1-XPF Interfaces to Identify Therapeutically Non-Resistant Small Anti-Cancer Compounds

OP76

Ciğdem KANBEŞ-DİNDAR

Evaluating the Interaction Between The Antineoplastic Drug Bexarotene and Double-stranded DNA Using Electrochemical and Spectroscopic Methods

OP77

Ioannis PAPAZOGLOU

Computational RNA Aptamer Design: A Pipeline for Precise Targeting of Macromolecular Elements in the Pursuit of Treating Retinal Degeneration within the RETORNA – A HORIZON Europe Initiative

OP78

Tamerlan MAMMADOV

Synthesis Novel Artesunate-Benzothiophene Derivatives

OP79

Khaled A.N. ABUSHARKH

Design, synthesis and antiproliferative activities of new benzothiazole/ benzothiazole thiazolidine-2,4-dione derivatives as potential FOXM1 inhibitors

OP80

Şule EROL GÜNAL

Evaluation of Pharmacokinetic and Drug Likeliness Properties of Thiazolidine-4-one Derivatives

OP81

Sevgi SARIGÜL ÖZBEK

The Drug Likeliness Properties of Some Novel 2-Thiohydantoin Derivatives

OP82

Büşra ÖZTÜRK AYDIN

Organohalogen chalcones: Design, Synthesis, ADMET Prediction, Molecular Dynamics Study and Enzyme İnhibition Profiles

OP83

Hamdi ÖZKAN

Synthesis, Spectroscopic Characterizations of Novel Norchantarimide Derivates

OP84

İzbel KURTULDU

Novel Semi-Synthetic Gypsogenin Derivative and Anticancer Activity Against Caco-2 Cancer Cell Line

OP85

Sema TUGAY

Synthesis of a New Imidazole Derivate That Can ESIPT Radiation

OP86

Ömer Yusuf ARAZ

Nitroreductase Targeted Cancerous Cell Imaging with ESIPT-Based Probe

OP87

Hazal Nazlıcan ATALAY

Investigating The Therapeutic Activities of Novel Selagibenzophenone B Derivatives as PARP-1 Inhibitors in The Treatment of Castration-Resistant Prostate Cancer

OP88

Şaban TURAN

Synthesis of Low Molecular Weight Heparin and bis-amino acid conjugates for the Development of New Anticancer Agents

OP89

Amal A. AL-SHARABI

Synthesis, Characterization, Molecular Docking and Molecular Dynamics Simulations of Novel 2,5-Disubstituted-1,3,4-Thiadiazole Derivatives as Potential Cholinesterase/Monoamine Oxidase Dual Inhibitors for Alzheimer’s Disease

OP90

Sana SAFFOUR

Exploring Novel Quinoline-1,3,4-Oxadiazole Derivatives for Alzheimer: Design, Synthesis, In-Vitro and In-Silico Investigations

OP91

Kajeen Hassan JASİM

The Impact of Adrenalin Dysregulation on Mental Health in Internally Displaced Yazidi’s Women in Northern Iraq

OP92

Kajeen Hassan JASİM

The Biochemical Mechanism Underlying Cortisol Synthesis And Regulation: İmplications For Mental Health Disorders in İnternally Displaced Women in Northern Iraq

OP93

Raghad SHARBAJI

IL-23 as a Key Player In Psoriasis: New Approach For Psoriasis Treatment

OP94

Zafer BULUT

Antioxidant Activities of Chiral Thioureas Derived From Enantiopure Amines

OP95

Sümeyya KOLDAŞ

Synthesis of Chalcone-dimethyl 1,2,3-triazole-4,5-dicarboxlate Structures

POSTER PROGRAMME
Mirage I-II Hall

Poster no

Author

Title

P1

Zafer BULUT

Design and Evaluation of Anticholinesterase Activities of Chiral

1,3-Thiazolidine-4,5-dione Derivatives

P2

Sümeyya KOLDAŞ

Synthesis of 5-Amino-4-Carboxylate-1,2,3-triazole-Chalcone Structures

P3

Canay PERÇİN

Validation Of Stability Indicating HPLC Method For The Quantitative Determination of Spiramycin Compositions and Degradation Products In Pharmaceutical Products

P4

Koray KÖROĞLU

Development and Validation of RP-HPLC Method for the Determination of Impurities in Effervescent Tablets Containing the Active Ingredients Ascorbic Acid & Acetylcysteine, and Their Separation

P5

Safiye EMİRDAĞ

Synthesis and Characterization of New Vitamine K3 Analogues

P6

Fulya UYSAL

Oxymetazoline HCI 0.01% Paediatric Nasal Spray Product; Assay Method Transfer From High Performance Luquid Chromatography (HPLC) To Ultra Performance Luquid Chromatography (UPLC) For Higher Avantage

P7

Buse MORGÜLÜM

Investigating the Impact of Various Wet Granulation Techniques on Tablets Containing Antidiabetic Drugs for Diabetes Management: Influence on Tablet Compression Characteristics

P8

Kardelen TUĞRUL ÖZTÜRK

Development of A Hormon Drug Formulation via Solid Dispersion for Comparable Quality Characteristics to the Reference Product: A BCS Class II Perspective

P9

Ayşenur YALÇIN

Development and Validation of Stability-Indicating HPLC Method For The Simultaneous Determination of Active Ingredients From The Sartan Group in Combination with Hydrochlorothiazide

P10

Oya TEMİZ

Effects of Supercritical-CO2 Extraction on Antimicrobial Activities of Thyme (Thymus vulgaris) Dried at Different Temperatures and Times

P11

Sedanur UÇAN

Nitrosamine Risk Assessment of Nitrosamine Impurities in Pharmaceutical Oral Solid Dose

P12

Filiz DEMİR

Nitrosamine Analysis for Biguanide-Containing Drugs Indicated

for the Treatment of Type II Diabetes

P13

Damla ÖZDEMİR

Synthesis, Characterization and Bioactivity Investigation of Norcantarimide Derived Compounds with Anticancer Activity Potential on Colon Cancer

P14

Ayşegül KARAKÜÇÜK-İYIDOĞAN

Enantiopure Thiosemicarbazones: Synthesis, Characterization and Antiproliferative Activity

P15

Cansu Müşerref YENİCİ

Activity-based Chemotherapy: A Dual-locked Camptothecin Prodrug for Selective Treatment of Cancer Cells

P16

Dilara TOĞRUL

Synthesis of Novel N-Benzyl Substituted Asymmetric α-Amino Acid Derivatives

P17

Nejat ARÇELİK

First Large-Scale Synthesis of Duloxetine Hydrochloride in Türkiye

P18

Ehsan SAYYAH

Discovering Novel Resistance-Free Ret Tyrosine Kinase Inhibitors: Extensive Molecular Dynamics Trajectories for Successful and Accelerated Virtual Screening of Ultra Large Ligand Libraries Through Machine Learning-Trained QSAR, Dynamic Pharmacophore Models and Neural Relational Inference Analysis.

P19

Anwar ABUELRUB

In-Silico Study: Inhibition of WDR5/MLL1 Complex as a Therapeutic Target for Leukemia

P20

Berkan BOZKURT

The Role of Butyrylcholinesterase in Cell Depression

P21

Bedriye Seda KURŞUN AKTAR

Investigation of α-Glucosidase and α-Amylase Inhibitory Effects of Chalcone Compounds With Methyl Group Chalcones and Molecular Modeling Studies

P22

Seher AYDIN

Synthesıs of Potentıal Bıologıcal Actıve Compounds via The Indole Scaffold

P23

Şeyda Nur SAMANCI

Electrochemical Investigation of Niraparib: Voltammetric Assay in Human Serum using glassy carbon electrode and boron-doped diamond

P24

Tuncay HATIL

A Novel Assay HPLC Method Development and Validation for Evaluating Behavior in Retention Time Sensitivity of Peptide Molecule in Low Dosage Sublingual Tablets  

P25

Fatma HAN

PROPOFOL-PF 1% 200 mg/20 mL Emulsion for I.V. Injection/Infusion Essential Similarity Study

P26

Lalehan OKTAY

Targeting miRNA for Colorectal Cancer: In Silico Identification and De Novo Modeling of Oncogenic miR-135b for Small Molecule-Based Therapy

P27

Bandar A. ALYAMİ

2-Veratryl-3,7-dihydroxy-4-one Analogue of Coumarin: Phytochemical Compound with Antidiabetic Evaluation

P28

Merve KAYA

Determination of Optimum Process Parameters For A Scale-Up Operation with Pinaverium Bromide Tablets

P29

TOLGA ÖZBAY

Development and Validation of an Analytical Method for the Dissolution of Dasatinib in Tablet Dosage Form by Liquid Chromatography

P30

Murat IŞIK

Investigating the effect of film coatings on physical stability of magnesium supplement tablets including vitamins

P31

Hande GAYRETLİ

Devolopment and validation of a new stability-indicating RP-HPLC method for determination of terifllunomide in pharmaceutical dosage forms

P32

Elif AKÇİL

Photostability Comparison of the Drug Product Used for Reversal of Neuromuscular Blockade Caused by Rocuronium or Vecuronium and the Reference Product

P33

Asad RIZVI

Design of Quaternary Amorphous Solid Dispersions for Enhanced Dissolution of Pharmaceutical composition comprising Enzalutamide

P34

Emine Elçin ORUÇ-EMRE

Discovery of Novel 1,2,4-Triazole Derivatives From N-[4-(2-Hydrazinyl-2-Oxoethyl)-1,3-Thiazol-2-yl]Benzamides As Cholinesterase Inhibitors

P35

Merve YILDIRIM

Extractable-Leachables Analyses of Tigecycline 50mg IV Lyophilized Powder for Infusion Solution

P36

Ezgi TÜRKEŞ

A Stability Indicating Hplc Method For Assessing The Degradation Profile Of Oseltamivir Phosphate Powder For Oral Suspension Under Stress Conditions

P37

Yunus Emre TOPRAK

Benserazide derivative 2-amino-3-(4-hydroxyphenyl)-N’-(2,3,4-trihydroxybenzyl) Synthesis of propanehydrazide compound and its cytotoxic activity on CCD-1079Sk skin fibroblast cells determination

P38

Nurhan METAN

Method Optimization Study on Amount Determination and Content Uniformity In Enteric Coated Tablet Form Containing Bisacodyl

P39

Nida AYDOĞDU OZDOGAN

Nanomaterial-Based Electrochemical Sensor Development for Sensitive Determination of Cefditoren in Human Serum and Pharmaceutical Forms

P40

Şenel TEKE TUNÇEL

Design, Synthesis and Molecular Docking Studies of Novel 2-İmino-Thiazolidin-4-ones as Potential AChE Enzyme Inhibitors

P41

Robert CZARNOMYSY

Anticancer Effect of Novel Platinum(II) bis(thiosemicarbazone) Complex in Breast Cancer Cells

P42

Yağız Kaan OLCAY

An Efficient Approach for Clinical Development of a Generic Prolonged Release Dosage Form

P43

Duygu KONUKLU

Simultaneous Determination and Validation of Some Antioxidants in Infusion Solutions Using Hydrophilic Interaction Chromatography (HILIC)

P44

Büşra Seniha TURAN

Simplified Composition and Process Design for a Generic Alternative to a Complex Brand Product

P45

Cem Batuhan CEVLIK

Effect of Electrostatic Charge on The Characterization of Nebulization Solution Dosage Form Including SABA / Anticholinergic Combination as Fine Particle Dose (FPD)

P46

Justyna Magdalena HERMANOWICZA

MM-129 and indoximod combination as a new approach against colorectal cancer

P47

Hüseyin KEKEÇMUHAMMED

Three-Component Reaction of a Mildrum Acid, a 2‑Oxoaldehyde, and a Robenidine Derivatives for the Synthesis of Tetrasubstituted Imidazole Derivatives

P48

Ahenk Burcu KOPÇUK

The Stability Indicated HPLC Method Development For The Assay Analysis of Fampridine Extended-Release Tablet Dosage Form Used in The Treatment of Multiple Sclerosis and Its Validation

P49

Beata SİEKLUCKA

Influence of adenine rich diet on calciotropic hormones and mineral metabolism in experimental rat model of chronic kidney disease

P50

Ozan AYDIN

Formulatıon Design Of Bcs Class II Molecule

by Using Design of Experiment (Doe) And Quality by Design (Qbd)

P51

Elif Gözde GÖKKAYA

Applications of Molecular Modeling Approaches to Elucidate Binding Mechanism of Unusual Inhibitors of CA II Isoform of Carbonic Anhydrase

P52

Hüda ÇAY

Investigating The Influence of Lubrication on Tableting: A Study on Mg Stearate Effect on Compressibility and Tableting Characteristics

P53

Mert CİHAN

Development and Validation of a Sample Preparation Method From Soft Gelatin Capsules for Edta Determinatıon in HPLC-DAD

P54

Derya GENİŞ

Development and validation of High pressure liquid choromotography  method for  determination of Paracetamol and Ibuprofen in fixed dose combinations

P55

İrem AKGÜL

Synthesis of P-N Type Schiff Bases and Secondary Amines; Investigation of Antioxidant Properties of the Synthesised Molecules

P56

Merve DOGAN

Synthesis of Thioamides from Schiff Bases; Investigation of Antioxidant Activities of the Synthesized Molecules

P57

Özlem ÇAĞRICI

Pain Relief Gel

P58

Serdar KARAKURT

In Vitro and In Vivo Activity of Multilayer Nanofibrous Wound Dressing in the World of Wound Healing

P59

Ahmet ÇETİNKAYA

Design and Application of MIP-Based Electrochemical Sensor for Quantification of Apigenin in Plant-Derived Commercial Food Supplement

P60

Ahmet Buğra ORTAAKARSU

Evaluation of Acetylcholinesterase (AChE) Inhibitory Potentials of Novel 1,2,3-Triazolcarbamates by Computational Methods

P61

Haluk Samet KOÇAK

A Dual Enzyme Responsive Resorufin-based Photosensitizer for Highly Selective Photodynamic Therapy

P62

Çağan AĞTAŞ

Development and validation of stability-indicating UPLC-UV-MS tandem methods for related substances and assay analyses of lenalidomide

P63

Sude ÇETİN

Tailoring Mavacamten Derivatives for Cardiac Myosin S1 Inhibition: A Molecular Docking and AI-Driven ADMET Analysis

P64

Maide MEŞHUR

Phytochemicals of Crataegus monogyna as Prospective Neuroprotective Agents: Computational Evaluation of CASP-3 and TPK1 Inhibition

P65

Ayça SAYMAZ

A Biotin Receptor Targeted Activity-based Type I Photosensitizer

P66

Muhammed Fatih KARAKAYA

Potential Small Molecules Targeting an orphan receptor GPR26

P67

Leyla AKYÜZ

Laboratory Setup equipped with the latest technological developments

P68

Alper YILDIRIM

Synthesis of Triazole Compounds from Azide-derived Oxazolidinone Compounds

P69

Muhammet Eren ULUG

Targeting MKK3-MYC Interactions: Small-Molecule Modulators and their Impact on Breast Cancer (TNBC)-Related MYC Activation

P70

Ekrem YAŞAR

An Investigation of Effects of Mescaline and Its Derivatives on Serotonin (5-HT2A) Receptor Activation Using Molecular Modeling Approaches

P71

Makbule DEMİRCAN

Exploring Symphoricarpos albus as a Natural Source of GSK-3β Inhibitors: Molecular Docking Studies and ADMET Analysis

P72

Ayşe Edanur ALTUNDAĞ

In Silico Design of Damnacanthal Derivatives as Potent LIM Kinase Inhibitors: An AI-guided ADMET and Molecular Docking Investigation

P73

Ali DİŞLİ

Synthesis And Activity Study of Some New Choline Esterase Inhibitor Compounds

P74

Sarp Emre TURAN

Synthesis of a Novel Lysosome-Targeted HOCl Activatable Chemiluminescent Probe for Cancer Cell Imaging

P75

Kenan TÜTÜNCÜ

The Digital Phytochemist: Berberis crataegina’s Bioactive Compounds vs. Tau-tubulin Kinase-2

P76

Fatma BUDAK

Development of a user-friendly, cost-effective and sensitive method for upadacitinib analysis using two different electrodes

P77

Çağla AFŞİN

Evaluating the Versatility of a New High Molecular Weight HPC in Dual Active Diabetic Controlled Release Dosages

P78

Çağla AFŞİN

An Improvement Grade of Hypromellose for Industrial Scale CR Tablet Manufacturing

P79

Ayça MEHMETOĞLU AL

Preparation and Characterization of Folic Acid-Bound Biopolymer Nanoparticles

P80

Aykut KUL

Determination of heparan sulfate in topical formulations by LC-MS/MS

P81

Okan SEZGİN

Identifying Small Molecule Protein-Protein Interaction Inhibitors as Resistance-Free Anti-Cancer Therapeutics Targeting C-MET/HGF Interface Using A Hybrid Virtual Screening Algorithm

P82

Önder AKÇA

First Application of Filter Validation Stages in the World Veterinary Pharmaceutical Industry in Turkey

P83

Beril Şara GÖK

Design and Synthesis of Pyridazine-1,2,4triazol Heterocylic Entites 

P84

Özgecan ŞAVLUĞ İPEK

Synthesis and Antiproliferative Evaluation of Oxazole and Thiazole Substitute Lonidamine Derivatives

P85

Abd Al Rahman ASFOUR

Investigation of Cox1/2 Inhibition Effects And Molecular Modeling Studies On Novel 3,4,5-Trisubstituted Triazole Derivatives

P86

Sana SAFFOUR

Design, Synthesis, and Biological Activity Evaluation of Novel EAAT-2 Activator for Alzheimer’s Disease

P87

Hande Naz ŞERMET

Transdermal Drug Systems (TDS) Production Method Optimization

P88

Bahar TERZİOĞLU

The Effect of the Gel Formed with the Combination of Aloe vera and Cannabis sativa Seed Oil on Full-Thickness Excisional Wound Healing

P89

Berkay İLYAS

Investigation of the Effects of In Vitro Dissolution Studies on the Topical Suspension Type Drug Product

P90

Esin YAMAÇ

API Particle Size Effect on Oral Suspension Formulations

P91

Cansu ŞANLI

Development and Validation of Stability-Indicating Analytical Methods for Related Substances of Pomalidomide

P92

Layla SALİH

Impact of Thalassaemia on The Patient’s and Their Families

P93

Hileen M. HAJİ

 Prevalence and pathological role of Escherichia coli in urinary tract infections among patients in Duhok ,Iraq

P94

Younos BOUZIAN

Sunlight Intramolecular [2+2] Cycloaddition of Allyl 2-oxo-1,2-dihydroquinoline-4-carboxylate

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